References

Tamgadge A, Tamgadge S, Bhatt D, Bhalerao S, Pereira T, Padhye M. Bilateral dentigerous cyst in a non-syndromic patient: report of an unusual case with review of the literature. J Oral Maxillofac Pathol. 2011; 15:91-95
Ko KS, Dover DG, Jordan RC. Bilateral dentigerous cysts – report of an unusual case and review of the literature. J Can Dent Assoc. 1999; 65:49-51
Speight P, Fantasia JE, Neville BW. Odontogenic and non odontogenic developmental cysts. In: El-Naggar AK, Chan JKC, Grandis JR, Takata T, Slootweg PJ (eds). : WHO: IARC Publications; 2017
Freitas DQ, Tempest LM, Sicoli E, Lopes-Neto FC. Bilateral dentigerous cysts: review of the literature and report of an unusual case. Dentomaxillofac Radiol. 2006; 35:464-468
Gonzalez SM, Spalding PM, Payne JB, Giannini PJ. A dentigerous cyst associated with bilaterally impacted mandibular canines in a girl: a case report. J Med Case Rep. 2011; 5
Ziccardi VB, Eggleston TI, Schneider RE. Using fenestration technique to treat a large dentigerous cyst. J Am Dent Assoc. 1997; 128:201-205
Devi P, Bhovi TV, Mehrotra V, Agarwal M. Multiple dentigerous cysts. J Maxillofac Oral Surg. 2014; 13:63-66
Ustuner E, Fitoz S, Atasoy C, Erden I, Akyar S. Bilateral maxillary dentigerous cysts: a case report. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2003; 95:632-635
Shah N, Thuau H, Beale I. Spontaneous regression of bilateral dentigerous cysts associated with impacted mandibular third molars. Br Dent J. 2002; 192:75-76
Roberts MW, Barton NW, Constantopoulos G, Butler DP, Donahue AH. Occurrence of multiple dentigerous cysts in a patient with the Maroteaux-Lamy syndrome (Mucopolysaccharidosis, type VI). Oral Surg Oral Med Oral Pathol. 1984; 58:169-175
Kaushik A, Chaudhry A, Saluja P, Kumar M, Varshney M. Non-syndromic bilateral dentigerous cysts of maxillary and mandibular canines: a case series and review of literature. J Oral Maxillofac Surg Med Pathol. 2015; 27:562-566
Knights EM, Brokaw WC, Kessler HP. The incidence of dentigerous cysts associated with a random sampling of unerupted third molars. Gen Dent. 1991; 39:96-98
Cury SE, Cury MD, Cury SE Bilateral dentigerous cyst in a nonsyndromic patient: case report and literature review. J Dent Child (Chic). 2009; 76:92-96
Vassiliou LV, Lahiri S, Matthews SN. Non-syndromic bilateral dentigerous cysts with significant root resorption: a case report. Oral Surg. 2015; 8:59-62
Motamedi MH, Talesh KT. Management of extensive dentigerous cysts. Br Dent J. 2005; 198:203-206
Aher V, Chander PM, Chikkalingaiah RG, Ali FM. Dentigerous cysts in four quadrants: a rare and first reported case. J Surg Tech Case Rep. 2013; 5:21-26
Akay MC, Kaya E, Zeytinoğlu M. Treatment of nonsyndromic dentigerous cysts in primary dentition. Clin Cosmet Investig Dent. 2011; 3:17-23
Banderas JA, González M, Ramírez F, Arroyo A. Bilateral mucous cell containing dentigerous cysts of mandibular third molars: report of an unusual case. Arch Med Res. 1996; 27:327-329
Bansal R, Pawar CUS, Sarkar S, Barman I. Large bilateral dentigerous cyst – rare case report. Arch Dent Med Res. 2015; 1:60-64
Batra P, Roychoudhury A, Balakrishan P, Parkash H. Bilateral dentigerous cyst associated with polymorphism in chromosome 1qh+. J Clin Pediatr Dent. 2004; 28:177-181
Burton DJ, Scheffer RB. Serratia infection in a patient with bilateral subcondylar impacted third molars and associated dentigerous cysts: report of case. J Oral Surg. 1980; 38:135-138
Callaghan JH. Bilateral impaction of lower third molars in association with bilateral dentigerous cyst formation. A case report. Glasg Dent J. 1973; 4:36-38
Carter TG, Brar PS, Tolas A, Beirne OR. Off-label use of recombinant human bone morphogenetic protein-2 (rhBMP-2) for reconstruction of mandibular bone defects in humans. J Oral Maxillofac Surg. 2008; 66:1417-1425
Catania AF. Report and comment on an unusual case of multiple follicular cysts with a recurrence. Oral Surg Oral Med Oral Pathol. 1952; 5:895-906
Chew YS, Aghabeigi B. Spontaneous regression of bilateral dentigerous cysts: a case report. Dent Update. 2008; 35:63-65
Crinzi RA. Bilateral dentigerous cysts of the mandible. Oral Surg Oral Med Oral Pathol. 1982; 54
Cura N, Hanttash A, Inceoglu B, Orhan K, Oncul AMT. Dentigerous cysts in four quadrants of a nonsyndromic patient: case report and literature review. Oral Radiol. 2014; 31:49-58
De Biase A, Ottolenghi L, Polimeni A, Benvenuto A, Lubrano R, Magliocca FM. Bilateral mandibular cysts associated with cyclosporine use: a case report. Pediatr Nephrol. 2001; 16:993-995
Deshpande AN, Deshpande NC. Bilateral infected dentigerous cyst in a special child. J Cranio Max Dis. 2013; 2:54-58
Eidinger GB. Bilateral dentigerous cysts in the child patient. Report of a case and review of the literature. Univ Tor Dent J. 1989; 2:20-23
Farahani S, Lotfalian M. A pigmented dentigerous cyst in a patient with multiple dentigerous cysts of the jaws: a case report. J Contemp Dent Pract. 2007; 8:85-91
Fregnani ER, Perez DE, de Carvalho PA, Alves FA. Metachronous bilateral dentigerous cysts associated with permanent first molars. J Dent Child (Chic). 2008; 75:197-200
Gnanaselvi UP, Kamatchi D, Sekar K, Narayanan S. Nonsyndromic multiple dentigerous cyst: a rare clinical presentation. SRM J Res Dent Sci. 2016; 7:114-117
Goyal R, Kumar A, Saxena D, Biswas R. Maxillary sinus swelling in a child: clinical dilemma. BMJ Case Rep. 2010; 2010
Grewal HK, Batra R. Non syndromic bilateral dentigerous cysts – a case report. Int J Dent Clin. 2010; 2:49-51
Hansford JT, Kelsch RD, Wiltz M. Multiple radiolucencies of the jaws in a 6 year old. N Y State Dent J. 2015; 81:40-43
Henefer EP. Bilateral dentigerous cysts of the maxilla. Report of a case. Oral Surg Oral Med Oral Pathol. 1964; 17:296-298
Hiremath SS, Charantimath S, Byakodi R, Hiremath SS. Non-syndromic bilateral dentigerous cysts in a 7 year old child: report of a rare case. Int J Contemp Dent. 2011; 2:101-104
Imada TS, Neto VT, Bernini GF Unusual bilateral dentigerous cysts in a nonsyndromic patient assessed by cone beam computed tomography. Contemp Clin Dent. 2014; 5:240-242
Ishihara Y, Kamioka H, Takano-Yamamoto T, Yamashiro T. Patient with nonsyndromic bilateral and multiple impacted teeth and dentigerous cysts. Am J Orthod Dentofacial Orthop. 2012; 141:228-241
Ivy RH. Multiple dentigerous cysts: with special reference to occurrence in siblings. Ann Surg. 1939; 109:114-125
Jeon JY, Park CJ, Cho SH, Hwang KG. Bilateral dentigerous cysts that involve all four dental quadrants: a case report and literature review. J Korean Assoc Oral Maxillofac Surg. 2016; 42:123-126
Jia S, Li B. Osteosarcoma of the jaws: case report on synchronous multicentric osteosarcomas. J Clin Diagn Res. 2014; 8:ZD01-ZD013
Kannan N, Patil R, Sreenivasalu P. Bilateral maxillary dentigerous cysts – a case report. Int J Dent Clinics. 2010; 2:28-32
Kanth S, Rajkumar K, Krishnana R Bilateral dentigerous cyst in a nine year old child. SRM J Res Dent Sci. 2011; 2:76-78
Kashyap SK, Kumar A, Bhan C, Selvaraj S. Dentigerous cyst with unerupted teeth in bilateral maxilla with oro antral fistula with DM Type I: a case report and review of literature. Int J Contemp Med Res. 2016; 3:958-960
Lin HP, Wang YP, Chen HM, Cheng SJ, Sun A, Chiang CP. A clinicopathological study of 338 dentigerous cysts. J Oral Pathol Med. 2013; 42:462-467
Lung KE, Ganatra S, Robinson CE. Multiple multilocular dentigerous cysts with intra-osseous and extra-osseous third molar displacement: a case report. Oral Health. 2006; 96:20-29
Mahajan S, Raj V, Boaz K, George T. Non-syndromic bilateral dentigerous cysts of mandibular premolars: a rare case and review of literature. Hong Kong Dent J. 2006; 3:129-133
McDonnell DG. Bilateral dentigerous cysts. A case history. J Ir Dent Assoc. 1988; 34
Morais HHA, Dias TG, Vasconcellos RJ Bilateral mandibular dentigerous cysts: a case report. RGO-Revista Gaúcha de Odontologia. 2014; 62:299-304
Myers PB. Bilateral dentigerous cysts of the mandible. Br Dent J. 1943; 74:67-68
Naik PN, Kiran RA, Samata Y, Kumar VA. Non syndromic, bilateral, dentigerous cysts associated with inverted mandibular third molars: a case report. J Diagnostics. 2014; 1:1-5
Norris LH, Piccoli P, Papageorge MB. Multiple dentigerous cysts of the maxilla and mandible: report of a case. J Oral Maxillofac Surg. 1987; 45:694-697
O'Neil DW, Mosby EL, Lowe JW. Bilateral mandibular dentigerous cysts in a five-year-old child: report of a case. ASDC J Dent Child. 1989; 56:382-384
Prabhakar V, Sandhu SV. Nonsyndromic bilateral maxillary dentigerous cysts: review of literature and report of an unusual case. Int J Pediatr Otorhinolaryngol Extra. 2011; 6:5-8
Prasad LK, Chakravarthi PS, Sridhar M, Ramakumar Y, Kattimani V. Nonsyndromic bilateral maxillary and unilateral mandibular multiple dentigerous cysts in a young girl: report of a rare case. Int J Clin Pediatr Dent. 2010; 3:219-223
Reddy MP, Swamy KVN, Tavane PN, Malu K, Gupta PK. Non syndromic bilateral dentigerous cysts: an unusual case report. Int J Clin Dent Sci. 2011; 2:74-76
Rocha JF, Carvalho THL, Almeida-Neto LF, Hochuli-Vieira E, Gonçales ES. Bilateral dentigerous cyst in non-syndromic patient: case report and review of literature. Head Neck Oncol. 2014; 6
Saluja JS, Ramakrishnan MJ, Vinit GB, Jaiswara C. Multiple dentigerous cysts in a nonsyndromic minor patient: report of an unusual case. Natl J Maxillofac Surg. 2010; 1:168-172
Sands T, Tocchio C. Multiple dentigerous cysts in a child. Oral Health. 1998; 88:27-29
Sanjay CJ, David CM, Kaul R, Shilpa PS. Kissing dentigerous cysts involving mandibular canines: report of unusual case with review of literature. J Calif Dent Assoc. 2015; 43:29-33
Shetty UA, Bhandary S, D'Cruz AM. Dentigerous cyst associated with bilaterally impacted permanent mandibular canines: a report of a rare case. Int J Clin Prev Dent. 2014; 10:281-284
Shirazian S, Agha-Hosseini F. Non-syndromic bilateral dentigerous cysts associated with permanent second premolars. Clin Pract. 2011; 1
Singh M, Vijayanand Siddalingappa MN Achondroplasia and dentigerous cyst – a coincidental finding or any relationship?. J Clin Diagn Res. 2015; 9:ZL01-ZL02
Smith G. Two dentigerous cysts in the mandible of one patient. Case report. Aust Dent J. 1996; 41:291-293
Stanback JS The management of bilateral cysts of the mandible. Oral Surg Oral Med Oral Pathol. 1970; 30:587-591
Swain S, Sarath G. Dentigerous cyst of bilateral maxillary canines in a young child. Orissa J Otorhinolaryngol Head Neck Surg. 2014; 8:41-44
Swerdloff M, Alexander SA, Ceen RF, Ferguson FS. Bilateral mandibular dentigerous cysts in a seven-year-old child. J Pedod. 1980; 5:77-84
Tikekar S, Degwekar SS, Bhowate RR. Bilateral dentigerous cyst: an unusual case report and review of literature. J Indian Acad Oral Med Radiol. 2010; 22:116-118
Odontogenic cysts and tumors. In: Neville BW, Damn DD, Allen CM, Bouquot JE (eds). Philadelphia: WB Saunders; 1995
Regezi JA. Cyst and cystlike lesions. In: Regezi JA, Sciubba J, Pogrel MA (eds). Philadelphia: WB Saunders; 2000
Martínez-Pérez D, Varela-Morales M. Conservative treatment of dentigerous cysts in children: a report of 4 cases. J Oral Maxillofac Surg. 2001; 59:331-333
Yasuoka T, Yonemoto K, Kato Y, Tatematsu N. Squamous cell carcinoma arising in a dentigerous cyst. J Oral Maxillofac Surg. 2000; 58:900-905

Bilateral dentigerous cysts: an updated literature review and report of a case with associated root resorption

From Volume 45, Issue 11, December 2018 | Pages 1063-1082

Authors

Zehra Yonel

BDS, MFDS RCS(Ed), FHEA, BDS, MFDS (RCS Edin) (RCS Eng), PGCert, MPH (Hons), PhD

Department of Periodontology, Birmingham Dental Hospital, St Chad's Queensway, Birmingham B4 6NN, UK

Articles by Zehra Yonel

Arathi Papineni McIntosh

BSc, BDS, MFDS RCS(Edin)

Specialty Trainee in Oral Surgery, Department of Oral Surgery

Articles by Arathi Papineni McIntosh

Neil Donaldson

BDS, MFDS RCPSG

Specialty Trainee in Oral Surgery, Department of Oral Surgery, University of Birmingham

Articles by Neil Donaldson

Michael Murphy

BDS, MSc, FDS(OS)

Consultant in Oral Surgery, Department of Oral Surgery, University of Birmingham, School of Dentistry, 5 Mill Pool Way, Birmingham B5 7EG

Articles by Michael Murphy

Pankaj Taneja

BDS, MJDF RCS(Eng), MOralSurg(Eng) PG Cert

Oral Surgery Specialist, PhD Student, Department of Dentistry and Oral Health, Section of Orofacial Pain and Jaw Function, Aarhus University, Denmark

Articles by Pankaj Taneja

Abstract

Abstract: Dentigerous cysts, though common, rarely present bilaterally. The rarity of bilateral presentation is highlighted by a review of the literature which revealed a total of 77 published cases. This demonstrated that, although 29% were asymptomatic, 58% presented with swelling and 22% with pain. The majority of patients were treated with enucleation alone (73%); 17% were managed with marsupialisation, and 8% treated with a combination of surgical techniques. Of cases reported, 16% had resorption of adjacent teeth, with 8% describing resorption of permanent dentition. This highlights the importance of symptom recognition and appropriate radiographic investigation from the outset to allow prompt, appropriate treatment.

CPD/Clinical Relevance: Dentigerous cysts are the second most common type of odontogenic cyst, however, their bilateral presentation in a syndrome-free patient is rare. Early recognition of symptoms, knowledge of appropriate investigations and management options are vital for ensuring optimal patient outcome.

Article

A dentigerous cyst is an epithelial-lined cavity which surrounds the crown of an unerupted tooth at the cemento-enamel junction.1, 2 It is considered benign and is developmental in nature.3 Dentigerous cysts are the second most common odontogenic cysts following radicular cysts,4 with evidence suggesting that they account for 25% of all odontogenic cysts.5

Dentigerous cysts develop due to the accumulation of fluid between the reduced enamel epithelium and enamel of an unerupted tooth or within the enamel organ.6 The erupting tooth exerts pressure on the impacted follicle which obstructs venous outflow. This results in a serum transudate across the capillary wall causing elevated hydrostatic pressure and therefore pooling of fluid. This causes separation of the follicle from the crown, leading to formation of the cyst.6, 7 Given this mechanism, dentigerous cysts generally materialize during tooth development in young patients, with peak incidence in the second to fourth decades of life.3 The teeth most frequently associated with such cysts are mandibular third molars, followed by maxillary canines.4

Register now to continue reading

Thank you for visiting Dental Update and reading some of our resources. To read more, please register today. You’ll enjoy the following great benefits:

What's included

  • Up to 2 free articles per month
  • New content available