Jane F Setterfield

Mucosal and Salivary Biology Division, Dental Institute, King's College London and St John's Institute of Dermatology, Guy's and St Thomas's NHS Foundation Trust, London, UK

Return of the great pox

Now recognized as infection with the bacterium Treponema pallidum and known for centuries, a syphilis epidemic broke out among the soldiers of Charles VIII of France. In 1495 he invaded Naples, and by...