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Ozone, either in gaseous form or as ozonated water, has been available for use as a treatment for dental caries for a decade. This paper reviews the literature on the subject by examining the findings of publications in the peer review literature. Eighteen papers were identified by a literature search. From the review of these, it was concluded that, while some laboratory studies and some short duration clinical studies have suggested that ozone may be effective in the treatment of root caries or killing of oral micro-organisms, the clinical evidence for the use of ozone in treatment of caries is not compelling.
Clinical Relevance: It may be considered that there is presently no justification for the routine use of ozone in the treatment of caries.
Article
Ozone, first discovered in 1840, is a naturally occurring compound consisting of three oxygen atoms. It is found in nature in the form of a gas in the atmosphere in a concentration of 1–10 ppm1 where it has a role in the thermal structure of the stratosphere. It is well known as a disinfectant, powerful oxidant and antimicrobial agent, having been used in World War I for treating gas gangrene, infected wounds and the like. It is a strong oxidizer of cell walls and the cytoplastic membranes of bacteria, making it a bactericidal, antiviral and antifungal agent.2 However, it has been considered to lack the ability to discriminate between various targets in the environment and bacteria, potentially affecting the outcome of antibacterial treatment.3
Today, ozone is a useful disinfectant used in a variety of areas, including:
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