Isolated Periorbital Angio-Oedema Induced by Aspirin: A Case Report and Review of the Literature

From Volume 34, Issue 5, June 2007 | Pages 302-304

Authors

Raheela Rafiq

MBChB, FDS RCS, MRCS

SHO ENT Surgery, Walsall Manor Hospital, Moat Road, Walsall, West Midlands WS2 9PS, UK

Articles by Raheela Rafiq

Abstract

Periorbital angio-oedema may present as an isolated manifestation of aspirin intolerance and can be very alarming to the patient. This case describes a 38-year-old gentleman with such localized clinical features. Once considered an unusual phenomenon, review of the literature has revealed an increased frequency, possibly as a result of previous poor documentation. Clinical manifestations of nonsteroidal anti-inflammatory drugs (NSAIDs) intolerance, in particular periorbital angio-oedema and its associated symptoms, with proposed aetiology and pathogenesis, are discussed.

Article