References

Thoma KH, Goldman HM. Central myxoma of the jaw. Oral Surg Oral Med Oral Pathol. 1947; 33:532-540
Kansy K, Juergens P, Krol Z, Paulussen M, Baumhoer D, Bruder E Odontogenic myxoma: diagnostic and therapeutic challenges in paediatric and adult patients – a case series and review of the literature. J Craniomaxillofac Surg. 2012; 40:271-276
Simon EN, Merkx MA, Vuhahula E, Ngassapa D, Stoelinga PJ. Odontogenic myxoma: a clinicopathological study of 33 cases. Int J Oral Maxillofac Surg. 2004; 33:333-337
Lo Muzio L, Nocini P, Favia G, Procaccini M, Mignogna MD. Odontogenic myxoma of the jaws: a clinical, radiologic, immunohistochemical, and ultrastructural study. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1996; 82:426-433
Martinez-Mata G, Mosqueda-Taylor A, Carlos-Bregni R, de Almeida OP, Contreras-Vidaurre E, Vargas PA Odontogenic myxoma: clinico-pathological, immunohistochemical and ultrastructural findings of a multicentric series. Oral Oncol. 2008; 44:601-607
Noffke CE, Raubenheimer EJ, Chabikuli NJ, Bouckaert MM. Odontogenic myxoma: review of the literature and report of 30 cases from South Africa. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007; 104:101-109
Leiser Y, Abu-El-Naaj I, Peled M. Odontogenic myxoma – a case series and review of the surgical management. J Craniomaxillofac Surg. 2009; 37:206-209
Subramaniam SS, Heggie AA, Kumar R, Shand JM. Odontogenic myxoma in the paediatric patient: a review of eight cases. Int J Oral Maxillofac Surg. 2016; 45:1614-1617
Department of Health and Social Care. Ionising Radiation (Medical Exposure) Regulations 2017: guidance. https://www.gov.uk/government/publications/ionising-radiation-medical-exposure-regulations-2017-guidance (Accessed 29 October 2018)
Kaczmarzyk T, Mojsa I, Stypulkowska J. A systematic review of the recurrence rate for keratocystic odontogenic tumour in relation to treatment modalities. Int J Oral Maxillofac Surg. 2012; 41:756-767
Ribeiro Junior O, Borba AM, Alves CA, de Gouveia MM, Coracin FL, Guimaraes Junior J. Keratocystic odontogenic tumors and Carnoy's solution: results and complications assessment. Oral Dis. 2012; 18:548-557
Fabrizi L, Taylor GW, Canas B, Boobis AR, Edwards RJ. Adduction of the chloroform metabolite phosgene to lysine residues of human histone H2B. Chem Res Toxicol. 2003; 16:266-275
Barros RE, Dominguez FV, Cabrini RL. Myxoma of the jaws. Oral Surg Oral Med Oral Pathol. 1969; 27:225-236
National Institute for Health and Care Excellence (NICE). Suspected cancer: recognition and referral (NG12). https://www.nice.org.uk/guidance/ng12 (Accessed 29 October 2018)
Department of Health. Referral to treatment consultant-led waiting times rules suite. https://www.gov.uk/government/publications/right-to-start-consultant-led-treatment-within-18-weeks (Accessed 29 October 2018)
Santosa RE. Provisional restoration options in implant dentistry. Aust. 2007; 52:234-242

Odontogenic Myxoma of the Maxilla: Diagnostic Considerations, Surgical Resection and Prosthetic Rehabilitation

From Volume 45, Issue 10, November 2018 | Pages 985-990

Authors

Yehya EK Gamie

BDS, MFDS RCS(Ed)

Oral and Maxillofacial Surgery Trainee/Dental Surgeon, York Hospital/Aintree University Hospital, Liverpool, UK

Articles by Yehya EK Gamie

Zakareya Gamie

BSc(Hons), MBChB, MRCS, PGCert (Genomic Medicine)

PhD Student and Honorary Clinical Research Associate in Trauma and Orthopaedic Surgery, Newcastle University, UK

Articles by Zakareya Gamie

David Seymour

BChD, MFDS RCS(Ed), MSc ClinDen(Rest Dent) FDS RCS(Ed)

Specialty Trainee in Restorative Dentistry, Department of Restorative Dentistry, Leeds Dental Institute, Clarendon Way, Leeds LS2 9LU, UK

Articles by David Seymour

Paul H Whitfield

MBBS, BDS, FDS, FRCS

Consultant Oral and Maxillofacial Surgeon, York Hospital, Wigginton Road, York, North Yorkshire, YO31 8HE, UK

Articles by Paul H Whitfield

Abstract

A 15-year-old female with a history of orthodontic treatment was referred by her general dental practitioner (GDP) to the Oral and Maxillofacial Surgery (OMFS) department after noticing a right buccal maxillary swelling during a routine check-up. Examination and radiographic investigations revealed a lesion extending from UR3 to UR6 causing bony expansion with no evidence of root resorption. Following biopsy and histopathological analysis, a diagnosis of Odontogenic Myxoma (OM) was made. Treatment involved a segmental resection and fitting an immediate partial denture. Options for long-term rehabilitation include removable and implant-supported prostheses.

CPD/Clinical Relevance: This case highlights the importance of thorough clinical and radiographic examination, and joint treatment planning between the Restorative and OMFS departments.

Article

Odontogenic Myxoma (OM) was first described in 19471 and is a benign, locally invasive, non-metastasizing neoplasm of mesenchymal origin.2,3,4 It is rare and accounts for between 1% and 17.7% of odontogenic tumours.5 Occurring at any age, it is most common in the second and third decades of life, with a higher incidence in females and in the mandible.2,3,4,5,6 Many cases are detected during routine dental examinations.5,7 Features include slow and asymptomatic growth, tooth displacement and root resorption, delayed eruption, pain, facial asymmetry, cortical bone perforation and soft tissue invasion.2,3,4,5,6,7,8 Radiographically, OM may appear as unilocular or multilocular radiolucencies and are described as having a soap bubble, honeycomb or tennis racket appearance.3,4,,6,7,8

Register now to continue reading

Thank you for visiting Dental Update and reading some of our resources. To read more, please register today. You’ll enjoy the following great benefits:

What's included

  • Up to 2 free articles per month
  • New content available