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The fourth edition of the World Health Organization classification of head and neck tumours summarizes changes in odontogenic and maxillofacial tumours and reintroduces a chapter on odontogenic cysts that reclassifies calcifying odontogenic cystic tumours as calcifying odontogenic cysts based on lack of evidence to substantiate them as true neoplasms. This article presents an unusual case report of a calcifying odontogenic cyst treated successfully with enucleation in support of the view of recent classification.
CPD/Clinical Relevance: Calcifying odontogenic cysts are rare entities that can be managed successfully by enucleation, supporting the WHO position that these cysts are not neoplasms.
Article
The term calcifying odontogenic cyst (COC) was first used by Gorlin et al in 19621,2,3 to describe a new odontogenic cystic entity with a peculiar pathogenesis and histological features. In 1971 and again in 1992,4,5,6,7 the World Health Organization (WHO) listed this entity and described it as:
A non-neoplastic cystic lesion in which epithelial lining shows a well-defined basal layer of columnar cells, an overlying layer that is often many cells thick that may resemble stellate reticulum, and masses of ghost cells that may be in the epithelial cells lining the cyst or in the fibrous capsule. The ghost cells may become calcified. Dysplastic dentin may be laid down next to the basal cell layer of the epithelium.
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