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Oral ulceration in newly diagnosed leukaemic patient with undiagnosed sweet's syndrome Daniel Brierley David N Slater John Snowden Debbie Holt Anne Hegarty Dental Update 2024 42:6, 707-709.
Authors
DanielBrierley
BDS(Hons), MFDS
SHO Oral Medicine and Pathology, Oral Medicine Unit, Charles Clifford Dental Hospital, Sheffield
Sweet's syndrome is a relatively rare but important skin condition which can affect the oral cavity. Awareness of this reactive condition is important for dentists who work in hospitals, where it is most likely to present. This report summarizes one such case and aims to introduce the reader to Sweet's syndrome.
CPD/Clinical Relevance: Oral ulceration is a common condition occurring in medical inpatients for which oral and maxillofacial surgery and medicine senior house officers and specialists are often asked to review on the ward. An awareness of Sweet's syndrome is important as it is most likely to occur in this setting and may present with oral ulceration.
Article
In early 2011, a 53-year-old female patient with a 3-week history of oral ulceration was referred to Oral Medicine from Haematology at the Charles Clifford Dental Hospital. There was no history of ulceration before this episode. A few weeks previously she had presented to another hospital with a sore throat and skin lesions on her face, neck, legs and forearms. The patient had also been aware of ulcers on her palate and throat during this period. At this time, a full blood count showed haemoglobin to be 7.6g/dL, a raised WCC count of 48.9 x 109/L and neutrophil count of 22.5 x 109/L with blast cells on blood film examination (0.56 X 109/L). She had pyrexia during the following weeks, constant leukocytosis and low platelets ranging from 7 to 134 x 109/L. After extensive work-up she was diagnosed as having acute leukaemia.
Her previous medical history revealed that she had controlled hypertension and asthma, with an allergy to penicillin. She was a non-smoker and drank a minimal amount of alcohol. She worked as a school teacher and was married with two children.
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