References

Gerasimidou O, Watson T, Millar B Effect of placing intentionally high restorations: randomized clinical trial. J Dent. 2016; 45:26-31 https://doi.org/10.1016/j.jdent.2015.11.006
Michelotti A, Farella M, Gallo LM Effect of occlusal interference on habitual activity of human masseter. J Dent Res. 2005; 84:644-648 https://doi.org/10.1177/154405910508400712
Le Bell Y, Jamsa T, Korri S Effect of artificial occlusal interferences depends on previous experience of temporomandibular disorders. Acta Odontol Scand. 2002; 60:219-222 https://doi.org/10.1080/000163502760147981
Durham J, Wassell RW Recent advancements in temporomandibular disorders (TMDs). Rev Pain. 2011; 5:18-25 https://doi.org/10.1177/204946371100500104
Ferro K, Morgano M, Driscoll C The glossary of prosthodontic terms ninth edition. J Prosthet Dent. 2017;
Goodman P, Greene CS, Laskin DM Response of patients with myofascial pain-dysfunction syndrome to mock equilibration. J Am Dent Assoc. 1976; 92:755-758 https://doi.org/10.14219/jada.archive.1976.0419
Ramfjord SP Bruxism, a clinical and electromyographic study. J Am Dent Assoc. 1961; 62:21-44 https://doi.org/10.14219/jada.archive.1961.0002
Koh H, Robinson PG Occlusal adjustment for treating and preventing temporomandibular joint disorders. Cochrane Database Syst Rev. 2003; https://doi.org/10.1002/14651858.CD003812
Tsukiyama Y, Baba K, Clark G An evidence-based assessment of occlusal adjustment as a treatment for temporomandibular disorders. J Prosthet Dent. 2001; 86:57-66
James M, Oluwajana F, Foster-Thomas E Temporomandibular disorders. Part 4: appliance therapy. Dent Update. 2022; 49:536-544
Marbach JJ Phantom bite. Am J Orthod. 1976; 70:190-199 https://doi.org/10.1016/s0002-9416(76)90319-5
Imhoff B, Ahlers MO, Hugger A Occlusal dysesthesia. A clinical guideline. J Oral Rehabil. 2020; 47:651-658 https://doi.org/10.1111/joor.12950
Cairns B, List T, Michelotti A JOR-CORE recommendations on rehabilitation of temporomandibular disorders. J Oral Rehabil. 2010; 37:481-489 https://doi.org/10.1111/j.1365-2842.2010.02082.x
Janson G, Crepaldi MV, Freitas KM Stability of anterior open-bite treatment with occlusal adjustment. Am J Orthod Dentofacial Orthop. 2010; 138:14e11-17 https://doi.org/10.1016/j.ajodo.2010.01.023
Banerji S, Mehta SB The direct canine rise restoration.Oxford: Wiley Blackwell; 2017
Murray M, Brunton P, Osborne-Smith K, Wilson N Canine risers: indications and techniques for their use. J Prosthodont Restor Dent. 2001; 9:137-140
Manfredini D, Poggio C Prosthodontic planning in patients with temporomandibular disorders and/or bruxism: a systematic review. J Prosthet Dent. 2017; 117:606-613
Turp JC, Strub JR Prosthetic rehabilitation in patients with temporomandibular disorders. J Prosthet Dent. 1996; 76:418-423 https://doi.org/10.1016/s0022-3913(96)90548-x
Türp J, Schindler H The dental occlusion as a suspected cause for TMDs: epidemiological and etiological considerations. J Oral Rehabil. 2012; 39:502-512
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Kanno T, Carlsson GE A review of the shortened dental arch concept focusing on the work by the Kayser/Nijmegen group. J Oral Rehabil. 2006; 33:850-862 https://doi.org/10.1111/j.1365-2842.2006.01625.x
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Temporomandibular disorders. Part 6: related irreversible restorative interventions

From Volume 49, Issue 9, October 2022 | Pages 705-710

Authors

Martin James

Specialty Registrar in Restorative Dentistry, University Dental Hospital of Manchester

Articles by Martin James

Charles Crawford

Lead Clinician TMD Clinic, University Dental Hospital of Manchester

Articles by Charles Crawford

Peter Clarke

DCT in Restorative Dentistry, Liverpool University School of Dentistry, Pembroke Place, Liverpool L3 5PS, UK (pete.t.clarke@gmail.com)

Articles by Peter Clarke

Funmi Oluwajana

Specialty Registrar in Restorative Dentistry, University Dental Hospital of Manchester; Clinical Fellow, Health Education England Northwest

Articles by Funmi Oluwajana

Email Funmi Oluwajana

Emma Foster-Thomas

Academic Clinical Fellow in Restorative Dentistry, University Dental Hospital of Manchester

Articles by Emma Foster-Thomas

Julian Satterthwaite

BDS, MSc, PhD, PGDip, PGCertHE, FDS, MFDS RCS, FDS(Rest Dent), FHEA, FADM, Professor and Honorary Consultant in Restorative Dentistry, University of Manchester

Articles by Julian Satterthwaite

Abstract

Considering the complex biopsychosocial nature of temporomandibular disorders (TMD), irreversible interventions of any kind should be used with extreme caution. Frequently they are reserved for those patients who have not achieved adequate control with reversible measures and in whom a significant improvement is anticipated. Irreversible restorative interventions range from the simple adjustment of a single restoration or tooth up to an occlusal equilibration, and may use a subtractive, additive or combined approach. This article, the last in a series of six, reviews the available evidence in the use of irreversible restorative interventions in the management of TMD, demonstrates some of the commonly used techniques and provides some guidance for the general dental practitioner (GDP) considering this approach.

CPD/Clinical Relevance: The GDP needs to be aware of when to, and more importantly when not to, consider making irreversible changes to a patient's dentition with the aim of managing their TMD.

Article

Until relatively recently, static and dynamic occlusal contacts were considered to be a major aetiological factor in temporomandibular disorders (TMD) and, therefore, predicated logic dictated that making changes to these could prevent and/or manage the condition. Even with the mounting evidence minimizing the role of occlusion in the biopsychosocial model of TMD, there are still many proponents for extensive irreversible therapies in its management.

There may be situations when it is appropriate to make additive and/or subtractive changes to the dentition as part of a management strategy for TMD. It is essential, however, that as these procedures are irreversible, the treating practitioner ensures that all reasonable conservative management strategies have been exhausted. There should also be a significant benefit expected from the intervention that outweighs the risks associated with many of these techniques.

This article reviews the evidence base for irreversible restorative interventions in relation to the management of TMD. This ranges from simple single-tooth adjustments to full-mouth rehabilitations, and examples are provided to demonstrate several techniques.

Localized occlusal adjustment

A localized occlusal interference may occur iatrogenically following placement of a non-conformative restoration, or due to tooth movement secondary to trauma, loss of periodontal support, or loss of an adjacent or opposing tooth. Most patients rapidly adapt to localized occlusal interferences and no lasting symptoms are reported.1,2 However, if changes to the articulatory system are outside a patient's adaptive capacity, the patient is likely to return with discomfort. A double-blind randomized controlled trial demonstrated that patients with a history of TMD were significantly more likely to have signs of TMD after placement of a small composite occlusal interference compared with a control group; patients with no history of TMD given the same interference were no different from controls.3 These results show the influence of adaptive capacity, highlighting that there is a group of patients predisposed to TMD who are less able to tolerate changes to their occlusion.

If TMD symptoms begin soon after the introduction of an occlusal interference, it would be warranted to adjust this interference. The occlusion, in this case, may be a precipitating or perpetuating factor in a patient who has a predisposition to TMD.4 This is a relatively simple procedure, but nonetheless should only be considered following a thorough history and a systematic occlusal assessment to identify the interference: this will be either a new deflective contact, around which the patient has to deviate, or a working/non-working side interference. This approach should only be considered where the diagnosis is certain and a maximum of two teeth require adjustment. Articulated study models and mock adjustments are not always required (Figure 1).

Figure 1. Localized occlusal adjustment. (a) Pre-operative view of showing static occlusal contacts in blue and a working-side interference/posterior guiding contact marked in red; this has caused fracture of the restoration. (b) Post-operative view with the interference/posterior guiding contact removed, cavity restored and static contacts marked in blue.

A case should be considered more akin to an equilibration in situations where: more than two teeth need adjusting to remove the interference; the temporal relationship between TMD onset and the creation of the interference is lacking; or the adjustment involves an intercuspal position contact (thereby reducing the occlusal vertical dimension, or rendering a tooth non-functional). Equilibrations require additional steps, training and experience. As with many concepts in dentistry, the boundary between localized occlusal adjustment and occlusal equilibration can be blurred, and if there is any doubt, there should be a low threshold for considering an adjustment as an equilibration with careful consideration and additional planning.

Occlusal equilibration

Occlusal equilibration is defined as the modification of the occlusal form of the teeth with the intent of equalizing occlusal stress, producing simultaneous occlusal contacts or harmonizing cuspal relations.5 Its role in the management of TMD has been debated for decades with many studies being of low quality. Effects shown range from complete resolution of symptoms with equilibration, to placebo/mock equilibration providing relief for the majority of patients.6,7 A Cochrane systematic review8 found no compelling evidence for occlusal equilibration in the routine management of TMD. Although the review only included three studies, these findings were corroborated by Tsukiyama et al9 whose study used more inclusive criteria to allow pooling of results from eleven studies with a wider range of methodology.

The lack of evidence for a benefit from occlusal equilibration is not equivalent to evidence of no benefit, but given the invasive and irreversible nature of this treatment, extreme caution needs to be exercised when considering this approach. A thorough history and examination of the masticatory system is of course required, as well as an exhaustive attempt at all conservative and appliance-based therapies. This will certainly include the construction, adjustment and monitoring of a well-made stabilization splint.

The ‘classic’ indication for an occlusal equilibration is a patient who achieves control of their TMD symptoms with a stabilization splint, but upon weaning, has return of symptoms. This indication is logical, but entirely anecdotal, and relies upon the assumption that the reason for symptomatic relief was purely due to creation of a removable ideal occlusion and not any of the other mechanisms by which the stabilization splint may be having an effect (see Part 4 of this series).10

Patients who are most definitely not candidates for occlusal equilibration are those who present with the complaint of a long-standing, ill-defined dissatisfaction with the way their teeth meet. The term ‘phantom bite’11 was first used to describe such patients who often have a history of multiple interventions by various clinicians in the pursuit of a solution. Several other terms have since been used, including occlusal hyperawareness, occlusal hypervigilance and occlusal dysaesthesia. The aetiology of this phenomenon is unclear, but is probably a combination of psychopathological influences, neuroplasticity, phantom phenomena and changes in proprioceptive stimuli and their transmission.12 Hypervigilance13 is a known behaviour in chronic pain where an individual is exceedingly aware of the sensory experience associated with a part of their body. This is fundamentally a psychological state of altered perception and, therefore, any physical intervention is doomed to failure.

Another patient group, relevant to TMD, who may benefit from equilibration are those with a deranged occlusion. In such situations, there is a change in the number or distribution of occlusal contacts that is the cause of an aesthetic or functional complaint. Equilibration for correction of an occlusal derangement should be approached with the same caution as any equilibration; it carries the same treatment risks (discussed below) and although the improvement in the occlusal scheme is immediate, it may not always be stable. Janson et al14 showed an overall relapse rate of 33% in their case series, with higher relapse rates for younger patients. However, their cohort had skeletal anterior open bites (AOB) that had relapsed following orthodontic treatment and a mean age of 21 years. These results may, therefore, not be generalizable.

A variety of factors, related and unrelated to TMD, can cause a deranged occlusion (Table 1) and the clinician should investigate potential non-TMD causes and refer to a medical specialist where appropriate.


Related to TMD Not related to TMD
Iatrogenic
  • Partial coverage splints
  • TMJ replacement surgery
  • Iatrogenic
  • Orthodontic/orthognathic relapse
  • Radiotherapy
  • Neuromuscular
  • Change in muscular tone which affects the rest position of the condyle
  • Traumatic
  • Mandibular fracture
  • Arthrogenic
  • Erosion of condyle head in osteoarthritis
  • Changes in positioning of the articular disk whereby the condyle sits on a thicker/thinner aspect of it
  • TMJ dislocation
  • Neurological
  • Multiple sclerosis
  • Hormonal
  • Acromegaly
  • Neoplastic
  • Tumour in the TMJ region
  • Idiopathic Idiopathic

    The process for undertaking an occlusal equilibration requires:

  • Confirmation that the mandibular position is stable;
  • Construction of accurate study models articulated in a position where the mandible is operating a purely rotational movement (on the terminal hinge axis/in centric relation);
  • Mock equilibration of the articulated study models (Figure 2);
  • Analysis of the volume of tooth structure sacrificed and the result achieved;
  • Detailed discussion with the patient to ensure valid consent is given with knowledge of the risks, benefits and alternatives;
  • Equilibration of the dentition by removal of tooth structure as per the mock equilibration;
  • Regular review, minor adjustments and management of complications.
  • Figure 2. Mock equilibration investigation. Study models: (a) frontal and (b) lateral. Mock equilibration view: (c) frontal; (d) lateral; (e) upper occlusal; and (f) lower occlusal showing the reduction of the anterior open bite and increase in the number of occluding pairs. Note the adjusted areas can be identified where the coloured spray has been removed.

    Examples of occlusal equilibrations undertaken for deranged occlusions due to neuromuscular changes (Figures 3) and TMJ replacement surgery (Figure 4) are presented.

    Figure 3. Occlusal equilibration to reduce an anterior open bite caused by changes in neuromuscular tone. Pre-operative view:(a) frontal and (b) lateral. Post-operative view: (c) frontal and (d) lateral showing the reduction of the anterior open bite and increase in the number of occluding pairs.
    Figure 4. Occlusal equilibration for a patient undergoing TMJ replacement surgery. Pre-operative view: (a) frontal and (b) lateral. Post-operative views following TMJ replacement surgery: (c) frontal and (d) lateral. Note the slight right-side lateral open bite. Post-operative views following occlusal equilibration: (e) frontal and (f) lateral. Post-operative rehabilitation with a two-part maxillary cobalt–chrome denture: (g) frontal and (h) lateral.

    Additive changes to the occlusal scheme

    Considering the not inconsequential risks associated with an occlusal equilibration, additive techniques could be considered to achieve some or all of the same goals. These techniques range from the addition of direct resin composite to key teeth, a common example being canine risers (Figure 5),15,16 to a complete reorganization of the occlusion using direct and/or indirect restorations. A full appraisal of all the various restorative techniques that could be employed and their respective failure and complication rates is outside the scope of this article, but it must be stressed that, as with any restorative treatment, especially if extensive, the maintenance requirements must be considered.

    Figure 5. Canine riser. (a) Pre-operative view. Note the wear facet caused by lateral guidance on the peg-shaped lateral incisor that is to be restored. (b) Post-operative view showing the lateral guidance, marked in green, moved to the canine with addition of direct composite.

    Considering the dearth of evidence for the efficacy of occlusal equilibration in the management of TMD, the evidence for occlusal rehabilitation with fixed restorations is even more scarce and, therefore, to justify the reorganization of a patient's occlusal scheme as a treatment would be a significant leap of faith.17,18 There are patients who would benefit from a full-mouth reconstruction for prosthodontic reasons who also have a TMD. Following successful conservative treatment of the TMD, this small group should be provided with a prosthodontically ideal occlusion, but with no promise that this will prevent future symptoms. The management of these patients can be extremely difficult due to their reduced adaptive capacity for occlusal change and, therefore, will often involve a pre-treatment appliance and an extended period of provisionalization.17

    Additive techniques can be used for replacement of missing teeth, and there is research to demonstrate an association between reduced posterior support, through missing posterior units, and TMD symptoms.19 It has been postulated that such patients posture their mandible to gain better masticatory function.20 This theory, however, goes against the large body of evidence that for the majority of patients a shortened dental arch of the anterior teeth and at least four occluding premolar-sized units is no different from an intact dentition for masticatory ability, signs and symptoms of TMD, migration of teeth, periodontal support and oral comfort.21,22 There may be individual patients for whom this is not the case and who may benefit from the replacement of posterior support, but this decision must be made on its own merits and not with the intention that this will manage a TMD. To reinforce this point, a multi-centre randomized controlled trial of shortened dental arch compared with the provision of precision attachment-retained removable partial dentures to replace missing posterior units, found no significant difference in TMD signs or symptoms between the groups at any recall up to 5 years.23

    Additive and subtractive changes to the occlusal scheme can sometimes be used in combination to achieve a desirable result while minimizing the negative consequences of either treatment in isolation. Each suitable case is likely to be unique and, therefore, there are no guidelines or evidence to guide the clinician and, as such, the patient needs to understand the unpredictable nature of such a plan. This approach has an extremely high level of complexity. Any clinician considering this treatment modality needs to be confident that they fully understand the process, have experience of simpler cases, and thoroughly plan the end result. Figure 6 illustrates a case where a combined approach was taken.

    Figure 6. Rehabilitation with a combined subtractive and additive approach to modifying the occlusal scheme. Pre-operative view: (a) frontal and (b) lateral. Mock equilibration showing bilateral canine contact with only significant adjustment to the UR7, which had a guarded long-term prognosis: (c) upper occlusal and (d) lower occlusal. Post-operative views following subtractive equilibration and additive restorations: (e) frontal; (f) lateral; (g) upper occlusal; and (h) lower occlusal. Note the thick metal coverage of the UL6 palatal cusp to achieve contact with the LL6.

    Conclusion

    All of the treatment modalities discussed above, no matter how minor, are irreversible in the sense that once completed, it would be impossible to return to the pre-treatment state. This is obviously true of subtractive methods, but also for additive, as even with careful removal of a restorative material the clinician is unlikely to ever be able to recreate a patient's pre-existing static and dynamic contacts to the level of accuracy detectable by the articulatory system, particularly so in patients with hypervigilance.

    Owing to the biopsychosocial nature of TMD, the use of an irreversible biological therapy in its management must always be considered a last resort option following an exhaustive attempt at conservative measures. The evidence base does not suggest that occlusion is a significant factor in the general population of TMD sufferers and would not support routine use of any irreversible occlusal therapy. That being said, for a small group of patients where occlusal discrepancies are considered a precipitating or perpetuating factor, occlusal changes could be justified. It is, however, challenging to confidently identify such patients among the crowd, and that is why a second opinion would always be prudent.

    Any clinician embarking upon an irreversible restorative intervention in relation to TMD needs to satisfy themselves that they have the appropriate knowledge, training and experience to justify the procedure, undertake the detailed planning required, carry out the clinical stages, and manage the consequences and complications that may arise.