References
A case of extensive oral kaposi's sarcoma in a patient with undiagnosed HIV infection
From Volume 45, Issue 4, April 2018 | Pages 360-362
Article
Kaposi's sarcoma is a low grade, soft tissue tumour of vascular endothelial origin. In 71% of cases, it presents with cutaneous and visceral involvement and most commonly arises amongst the male population.1,2 In 1994, Chang and colleagues identified a new herpesvirus (HHV-8) which was at the time linked with over 95% of Kaposi's sarcoma (KS) lesions identified.3 Although infection with the HHV-8 virus is now considered necessary for development of the tumour, it is not sufficient alone, and a variety of other co-factors appear also to be involved.4
Infection with HIV is one such co-factor and the incidence of KS is approximately 1 in 20 amongst individuals infected with HIV.5 In around 22% of cases, KS manifests with oral involvement as its first presentation.2
Here the case of a patient who presented with oral, cutaneous and visceral lesions associated with KS is discussed on a background of undiagnosed HIV infection.
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