References

Bharti AH, Chotaliya K, Marfatia YS. An update on oral human papillomavirus infection. Indian J Sex Transm Dis AIDS. 2013; 34:77-82 https://doi.org/10.4103/0253-7184.120533
Hassan Saad R, Halawa SM, Zidan AM Malignant transformation of oral squamous cell papilloma: a case report. Int J Surg Case Rep. 2020; 75:348-351 https://doi.org/10.1016/j.ijscr.2020.09.064
Syrjänen S. Oral manifestations of human papillomavirus infections. Eur J Oral Sci. 2018; 126 Suppl:49-66 https://doi.org/10.1111/eos.12538
Benyo S, Keane A, Warrick J, Choi KY. HPV-positive oral papillomas in an adolescent. A diagnostic dilemma. Clin Case Rep. 2021; 9 https://doi.org/10.1002/ccr3.4546

Letters to the Editor

From Volume 50, Issue 3, March 2023 | Pages 222-223

Authors

Alisha Amin

Dental Core Trainee

Articles by Alisha Amin

Farzana Hakim

Staff grade

Articles by Farzana Hakim

Shadaab Mumtaz

BDS, MFDS, RCPS (Glasg), ORE

Department of Oral and Maxillofacial Surgery, Royal Free London, NHS Foundation Trust, London, UK

Articles by Shadaab Mumtaz

Article

We saw a 73-year-old man in September 2020, who was referred by his GP for multiple lumps on his tongue and lower lip of unknown duration. His past medical history was significant for ischaemic heart disease, COPD, asthma, osteopenia and chronic kidney disease. He smoked 20 cigarettes a day (50 pack-years) and did not drink alcohol regularly.

On examination there was no obvious cervical lymphadenopathy. Multiple painless pedunculated papillomatous lumps of the lower lip, anterior mandibular ridge and ventral/dorsum of the tongue were noted (Figure 1).

Excisional biopsies of these lesions and subsequent histopathological evaluation revealed multiple papillomatous lesions suggestive of a viral aetiology. Genotype testing confirmed human papilloma virus (HPV), X09/11 presence (low risk). Unfortunately, this patient attended again in October 2021 with recurrence of lesions and further excision of these lumps was undertaken. The results confirmed the earlier diagnosis with no sinister changes. He was seen again in November 2022 with further recurrence of lesions in the same sites noted earlier. The patient was referred to the infectious diseases team for further assessment and management of these morbid recurrent lesions.

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