This article, the first part of a two-part review, has outlined genetic/developmental disorders, specific infections and inflammatory and immune conditions that can affect the gingival tissues....

A 19-year-old male was referred in urgently by their general dental practitioner to the Oral Medicine department. The patient was initially seen in September 2018 and complained of a 2-month history...

The active chemicals in all vaccines and other medications can change in molecular form when exposed to different temperatures, and the front-running Covid-19 vaccines from Pfizer and Moderna will be...

The majority of cases of SSC in the mouth arise in what was previously clinically normal tissue. However, some cancers are known to develop within a pre-existing mucosal abnormality and a list of such...

Numerous studies have explored the reasons for delayed presentation of oral cancer. There are two main causes for delays in cancer presentation (Figure 1):.

A 10-year-old boy was referred to the Joint Paediatric-Oral Medicine clinic with a five-month history of an erythematous ‘spongy’ lesion involving the gingiva of the upper left central incisor. The...

On presentation, the patient did not have any complaints relating to the objects present in the head and neck region as they were entirely asymptomatic. The patient reported being unaware of their...

Trigeminal neuralgia is considered to be a rare disease and the estimated prevalence from an old study in the USA put it at 4.1/10,000.2 More recent studies in the UK3 and Holland,4 using data from...

A 27 year-old male presented to the University Hospital of South Manchester maxillofacial department with a five year history of a large lump in the left palate. The patient reported that there was no...

The pathogenesis is a T cell-mediated autoimmune reaction. Once activated, these cells migrate to the oral epithelium aided by specific signalling pathways (CXR3 and CCR5). This is compounded by...

A 52-year-old male reported to the University of British Columbia Nobel Biocare Oral Health Center (Vancouver, BC, Canada) for general dental care and maintenance. Medical history indicated that, at...

From 2012 to 2016, five patients with oral lymphoma presented to the Oral Medicine Department at Charles Clifford Dental Hospital. The patients were of an elderly age group, in their seventh and...

Cases of primary malignant oral melanoma account for 0.2–8% of all melanomas.5 Most POMs arise in previously clinically normal mucosa, while approximately 30–50% of cases have had pre-existing oral...

A 55-year-old male was referred to the Oral and Maxillofacial Surgery (OMFS) Department at St George's Hospital by his general dental practitioner for further investigations of an incidental finding...

A 25-year-old male presented to the Emergency Department of Royal Gwent Hospital with a 6 day history of dyspnoea, severe headaches and a self-terminating episode of supraventricular tachycardia...